Sublingual targeting of STING with 3′3′-cGAMP promotes systemic and mucosal immunity against anthrax toxins

Anthrax is caused by Bacillus anthracis, a zoonotic bacterial pathogen affecting humans and livestock worldwide. The current human anthrax vaccine, anthrax vaccine adsorbed (AVA), is an injected vaccine with a cumbersome administration schedule and fails to promote mucosal immunity. Bacterial entero...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Vaccine
Prif Awduron: Martin, Tara L., Jee, Junbae, Kim, Eunsoo, Steiner, Haley E., Cormet-Boyaka, Estelle, Boyaka, Prosper N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719503/
https://ncbi.nlm.nih.gov/pubmed/28343781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2017.02.064
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