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Roles of two types of heparan sulfate clusters in Wnt distribution and signaling in Xenopus

Wnt proteins direct embryonic patterning, but the regulatory basis of their distribution and signal reception remain unclear. Here, we show that endogenous Wnt8 protein is distributed in a graded manner in Xenopus embryo and accumulated on the cell surface in a punctate manner in association with “N...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Mii, Yusuke, Yamamoto, Takayoshi, Takada, Ritsuko, Mizumoto, Shuji, Matsuyama, Makoto, Yamada, Shuhei, Takada, Shinji, Taira, Masanori
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719454/
https://ncbi.nlm.nih.gov/pubmed/29215008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02076-0
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