An advanced BLT-humanized mouse model for extended HIV-1 cure studies

OBJECTIVE: Although BLT-humanized mice provide a robust model for HIV-1 infection and enable evaluation of cure strategies dependent on endogenous immune responses, most mice develop graft versus host disease (GVHD), limiting their utility for extended HIV cure studies. This study aimed to: 1) Evalu...

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Udgivet i:AIDS
Main Authors: LAVENDER, Kerry J., PACE, Craig, SUTTER, Kathrin, MESSER, Ronald J., POUNCEY, Dakota L., CUMMINS, Nathan W., NATESAMPILLAI, Sekar, ZHENG, Jim, GOLDSMITH, Joshua, WIDERA, Marek, VAN DIS, Erik S., PHILLIPS, Katie, RACE, Brent, DITTMER, Ulf, KUKOLJ, George, HASENKRUG, Kim J.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718929/
https://ncbi.nlm.nih.gov/pubmed/29112072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001674
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