Concurrent administration of IFNα14 and cART in TKO-BLT mice enhances suppression of HIV-1 viremia but does not eliminate the latent reservoir

Combination antiretroviral therapy (cART) prevents HIV-1 replication but does not eliminate the latent reservoir and cure the infection. Type I interferons (IFN) mediate antiviral effects through different mechanisms than cART. We previously showed that IFNα14 is the most potent IFNα subtype against...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sutter, Kathrin, Lavender, Kerry J., Messer, Ronald J., Widera, Marek, Williams, Katie, Race, Brent, Hasenkrug, Kim J., Dittmer, Ulf
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889145/
https://ncbi.nlm.nih.gov/pubmed/31792317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54650-9
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