DNA vaccines elicit durable protective immunity against individual or simultaneous infections with Lassa and Ebola viruses in guinea pigs

We previously developed optimized DNA vaccines against both Lassa fever and Ebola hemorrhagic fever viruses and demonstrated that they were protective individually in guinea pig and nonhuman primate models. In this study, we vaccinated groups of strain 13 guinea pigs two times, four weeks apart with...

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Dettagli Bibliografici
Pubblicato in:Hum Vaccin Immunother
Autori principali: Cashman, Kathleen A., Wilkinson, Eric R., Wollen, Suzanne E., Shamblin, Joshua D., Zelko, Justine M., Bearss, Jeremy J., Zeng, Xiankun, Broderick, Kate E., Schmaljohn, Connie S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
Soggetti:
Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718824/
https://ncbi.nlm.nih.gov/pubmed/29135337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2017.1382780
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