DNA vaccines elicit durable protective immunity against individual or simultaneous infections with Lassa and Ebola viruses in guinea pigs

We previously developed optimized DNA vaccines against both Lassa fever and Ebola hemorrhagic fever viruses and demonstrated that they were protective individually in guinea pig and nonhuman primate models. In this study, we vaccinated groups of strain 13 guinea pigs two times, four weeks apart with...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Cashman, Kathleen A., Wilkinson, Eric R., Wollen, Suzanne E., Shamblin, Joshua D., Zelko, Justine M., Bearss, Jeremy J., Zeng, Xiankun, Broderick, Kate E., Schmaljohn, Connie S.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718824/
https://ncbi.nlm.nih.gov/pubmed/29135337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2017.1382780
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