DNA vaccines elicit durable protective immunity against individual or simultaneous infections with Lassa and Ebola viruses in guinea pigs

We previously developed optimized DNA vaccines against both Lassa fever and Ebola hemorrhagic fever viruses and demonstrated that they were protective individually in guinea pig and nonhuman primate models. In this study, we vaccinated groups of strain 13 guinea pigs two times, four weeks apart with...

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Vydáno v:Hum Vaccin Immunother
Hlavní autoři: Cashman, Kathleen A., Wilkinson, Eric R., Wollen, Suzanne E., Shamblin, Joshua D., Zelko, Justine M., Bearss, Jeremy J., Zeng, Xiankun, Broderick, Kate E., Schmaljohn, Connie S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2017
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718824/
https://ncbi.nlm.nih.gov/pubmed/29135337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2017.1382780
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