Acute myeloid leukaemia at an early age: Reviewing the interaction between pesticide exposure and KMT2A-rearrangement

Acute myeloid leukaemia (AML) in early childhood is characterised by a high frequency of recurrent genomic aberrations associated with distinct myeloid subtypes, clinical outcomes and pathogenesis. Genomic instability is the first step of pathogenic mechanism in early childhood AML. A sum of adverse...

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Vydáno v:Ecancermedicalscience
Hlavní autoři: Pombo-de-Oliveira, Maria S, Andrade, Francianne Gomes, Brisson, Gisele Dallapicola, dos Santos Bueno, Filipe Vicente, Cezar, Ingrid Sardou, Noronha, Elda Pereira
Médium: Artigo
Jazyk:Inglês
Vydáno: Cancer Intelligence 2017
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718248/
https://ncbi.nlm.nih.gov/pubmed/29225689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3332/ecancer.2017.782
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