CD44 Expression Profile Varies According to Maturational Subtypes and Molecular Profiles of Pediatric T-Cell Lymphoblastic Leukemia

CD44 is a glycoprotein expressed in leucocytes and a marker of leukemia-initiating cells, being shown to be important in the pathogenesis of T cell acute lymphoblastic leukemia (T-ALL). In this study, we have (i) identified the aberrant antigenic pattern of CD44 and its isoform CD44v6 in T-ALL; (ii)...

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Detalles Bibliográficos
Publicado en:Front Oncol
Main Authors: Marques, Luísa Vieira Codeço, Noronha, Elda Pereira, Andrade, Francianne Gomes, dos Santos-Bueno, Filipe Vicente, Mansur, Marcela B., Terra-Granado, Eugenia, Pombo-de-Oliveira, Maria S.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Oncology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6220090/
https://ncbi.nlm.nih.gov/pubmed/30430079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00488
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