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TSHR as a therapeutic target in Graves’ disease

Graves’ disease (GD) and its extrathyroidal manifestations such as thyroid-associated ophthalmopathy (TAO) are thought to result from abnormal activities of pathogenic antibodies mediated through the thyrotropin receptor (TSHR). At the core of GD is the loss of immune tolerance to TSHR and the gener...

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Detalhes bibliográficos
Publicado no:Expert Opin Ther Targets
Autor principal: Smith, Terry J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718165/
https://ncbi.nlm.nih.gov/pubmed/28127991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728222.2017.1288215
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