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TSHR as a therapeutic target in Graves’ disease

Graves’ disease (GD) and its extrathyroidal manifestations such as thyroid-associated ophthalmopathy (TAO) are thought to result from abnormal activities of pathogenic antibodies mediated through the thyrotropin receptor (TSHR). At the core of GD is the loss of immune tolerance to TSHR and the gener...

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Vydáno v:Expert Opin Ther Targets
Hlavní autor: Smith, Terry J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718165/
https://ncbi.nlm.nih.gov/pubmed/28127991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728222.2017.1288215
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