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Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis in the aged
Catecholamine-induced lipolysis, the first step in generation of energy substrates through hydrolysis of triglycerides (TGs) (1), declines with age (2,3). The defect in mobilization of free fatty acids (FFA) in elderly is accompanied with increased visceral adiposity, lower exercise capacity, failur...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5718149/ https://ncbi.nlm.nih.gov/pubmed/28953873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature24022 |
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