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An Environmentally Sensitive Fluorescent Dye as a Multidimensional Probe of Amyloid Formation

[Image: see text] We have explored amyloid formation using poly(amino acid) model systems in which differences in peptide secondary structure and hydrophobicity can be introduced in a controlled manner. We show that an environmentally sensitive fluorescent dye, dapoxyl, is able to identify β-sheet s...

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Veröffentlicht in:J Phys Chem B
Hauptverfasser: Yates, Emma V., Meisl, Georg, Knowles, Tuomas P. J., Dobson, Christopher M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2016
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5717618/
https://ncbi.nlm.nih.gov/pubmed/26865546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.5b09663
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