Wnt-induced Vangl2 phosphorylation is dose-dependently required for planar cell polarity in mammalian development

Planar cell polarity (PCP) is an evolutionarily conserved essential mechanism that provides directional information to control and coordinate polarized cellular and tissue behavior during embryonic development. Disruption of PCP leads to severe morphological defects in vertebrates and its dysregulat...

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Publicat a:Cell Res
Autors principals: Yang, Wei, Garrett, Lisa, Feng, Di, Elliott, Gene, Liu, Xilin, Wang, Ni, Wong, Yu Ming, Choi, Nga Ting, Yang, Yingzi, Gao, Bo
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5717403/
https://ncbi.nlm.nih.gov/pubmed/29056748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2017.127
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