Asymmetry of VANGL2 in migrating lymphocytes as a tool to monitor activity of the mammalian WNT/planar cell polarity pathway

BACKGROUND: The WNT/planar-cell-polarity (PCP) pathway is a key regulator of cell polarity and directional cell movements. Core PCP proteins such as Van Gogh-like2 (VANGL2) are evolutionarily highly conserved; however, the mammalian PCP machinery is still poorly understood mainly due to lack of suit...

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Vydáno v:Cell Commun Signal
Hlavní autoři: Kaucká, Markéta, Petersen, Julian, Janovská, Pavlína, Radaszkiewicz, Tomasz, Smyčková, Lucie, Daulat, Avais M, Borg, Jean-Paul, Schulte, Gunnar, Bryja, Vitezslav
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Methodology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314808/
https://ncbi.nlm.nih.gov/pubmed/25627785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-014-0079-1
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