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Vangl-dependent planar cell polarity signalling is not required for neural crest migration in mammals

The role of planar cell polarity (PCP) signalling in neural crest (NC) development is unclear. The PCP dependence of NC cell migration has been reported in Xenopus and zebrafish, but NC migration has not been studied in mammalian PCP mutants. Vangl2(Lp/Lp) mouse embryos lack PCP signalling and under...

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Bibliografische gegevens
Hoofdauteurs: Pryor, Sophie E., Massa, Valentina, Savery, Dawn, Andre, Philipp, Yang, Yingzi, Greene, Nicholas D. E., Copp, Andrew J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197537/
https://ncbi.nlm.nih.gov/pubmed/25038043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.111427
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