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Vangl-dependent planar cell polarity signalling is not required for neural crest migration in mammals

The role of planar cell polarity (PCP) signalling in neural crest (NC) development is unclear. The PCP dependence of NC cell migration has been reported in Xenopus and zebrafish, but NC migration has not been studied in mammalian PCP mutants. Vangl2(Lp/Lp) mouse embryos lack PCP signalling and under...

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Dettagli Bibliografici
Autori principali: Pryor, Sophie E., Massa, Valentina, Savery, Dawn, Andre, Philipp, Yang, Yingzi, Greene, Nicholas D. E., Copp, Andrew J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197537/
https://ncbi.nlm.nih.gov/pubmed/25038043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.111427
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