Inhibition of A(2A) Adenosine Receptor Signaling in Cancer Cells Proliferation by the Novel Antagonist TP455

Several evidences indicate that the ubiquitous nucleoside adenosine, acting through A(1), A(2A), A(2B), and A(3) receptor (AR) subtypes, plays crucial roles in tumor development. Adenosine has contrasting effects on cell proliferation depending on the engagement of different receptor subtypes in var...

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Bibliografski detalji
Izdano u:Front Pharmacol
Glavni autori: Gessi, Stefania, Bencivenni, Serena, Battistello, Enrica, Vincenzi, Fabrizio, Colotta, Vittoria, Catarzi, Daniela, Varano, Flavia, Merighi, Stefania, Borea, Pier Andrea, Varani, Katia
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Pharmacology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716981/
https://ncbi.nlm.nih.gov/pubmed/29249971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00888
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