Inhibition of A(2A) Adenosine Receptor Signaling in Cancer Cells Proliferation by the Novel Antagonist TP455

Several evidences indicate that the ubiquitous nucleoside adenosine, acting through A(1), A(2A), A(2B), and A(3) receptor (AR) subtypes, plays crucial roles in tumor development. Adenosine has contrasting effects on cell proliferation depending on the engagement of different receptor subtypes in var...

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Bibliografische gegevens
Gepubliceerd in:Front Pharmacol
Hoofdauteurs: Gessi, Stefania, Bencivenni, Serena, Battistello, Enrica, Vincenzi, Fabrizio, Colotta, Vittoria, Catarzi, Daniela, Varano, Flavia, Merighi, Stefania, Borea, Pier Andrea, Varani, Katia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2017
Onderwerpen:
Pharmacology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716981/
https://ncbi.nlm.nih.gov/pubmed/29249971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00888
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