Gastric myoelectric activity during cisplatin-induced acute and delayed emesis reveals a temporal impairment of slow waves in ferrets: effects not reversed by the GLP-1 receptor antagonist, exendin (9-39)

Preclinical studies show that the glucagon-like peptide-1 (GLP-1) receptor antagonist, exendin (9-39), can reduce acute emesis induced by cisplatin. In the present study, we investigate the effect of exendin (9-39) (100 nmol/24 h, i.c.v), on cisplatin (5 mg/kg, i.p.)-induced acute and delayed emesis...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lu, Zengbing, Ngan, Man P., Lin, Ge, Yew, David T.W., Fan, Xiaodan, Andrews, Paul L.R., Rudd, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716760/
https://ncbi.nlm.nih.gov/pubmed/29228720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21859
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