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Cisplatin-induced emesis: systematic review and meta-analysis of the ferret model and the effects of 5-HT(3) receptor antagonists

PURPOSE: The ferret cisplatin emesis model has been used for ~30 years and enabled identification of clinically used anti-emetics. We provide an objective assessment of this model including efficacy of 5-HT(3) receptor antagonists to assess its translational validity. METHODS: A systematic review id...

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Autores principales: Percie du Sert, N., Rudd, J. A., Apfel, C. C., Andrews, P. L. R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer-Verlag 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043247/
https://ncbi.nlm.nih.gov/pubmed/20509026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-010-1339-4
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