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Selective aggregation of the splicing factor Hsh155 suppresses splicing upon genotoxic stress

Upon genotoxic stress, dynamic relocalization events control DNA repair as well as alterations of the transcriptome and proteome, enabling stress recovery. How these events may influence one another is only partly known. Beginning with a cytological screen of genome stability proteins, we find that...

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Publicat a:J Cell Biol
Autors principals: Mathew, Veena, Tam, Annie S., Milbury, Karissa L., Hofmann, Analise K., Hughes, Christopher S., Morin, Gregg B., Loewen, Christopher J.R., Stirling, Peter C.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716266/
https://ncbi.nlm.nih.gov/pubmed/28978642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201612018
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