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Selective defects in gene expression control genome instability in yeast splicing mutants

RNA processing mutants have been broadly implicated in genome stability, but mechanistic links are often unclear. Two predominant models have emerged: one involving changes in gene expression that perturb other genome maintenance factors and another in which genotoxic DNA:RNA hybrids, called R-loops...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Mol Biol Cell
Main Authors: Tam, Annie S., Sihota, Tianna S., Milbury, Karissa L., Zhang, Anni, Mathew, Veena, Stirling, Peter C.
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Cell Biology 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589566/
https://ncbi.nlm.nih.gov/pubmed/30462576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-07-0439
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