Closed-loop control of targeted ultrasound drug delivery across the blood–brain/tumor barriers in a rat glioma model

Cavitation-facilitated microbubble-mediated focused ultrasound therapy is a promising method of drug delivery across the blood–brain barrier (BBB) for treating many neurological disorders. Unlike ultrasound thermal therapies, during which magnetic resonance thermometry can serve as a reliable treatm...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sun, Tao, Zhang, Yongzhi, Power, Chanikarn, Alexander, Phillip M., Sutton, Jonathan T., Aryal, Muna, Vykhodtseva, Natalia, Miller, Eric L., McDannold, Nathan J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715774/
https://ncbi.nlm.nih.gov/pubmed/29133392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1713328114
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