Adaptive benefits from small mutation supplies in an antibiotic resistance enzyme

Populations with large mutation supplies adapt via the “greedy” substitution of the fittest genotype available, leading to fast and repeatable short-term responses. At longer time scales, smaller mutation supplies may in theory lead to larger improvements when distant high-fitness genotypes more rea...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Salverda, Merijn L. M., Koomen, Jeroen, Koopmanschap, Bertha, Zwart, Mark P., de Visser, J. Arjan G. M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2017
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715772/
https://ncbi.nlm.nih.gov/pubmed/29133391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712999114
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