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Adaptive benefits from small mutation supplies in an antibiotic resistance enzyme

Populations with large mutation supplies adapt via the “greedy” substitution of the fittest genotype available, leading to fast and repeatable short-term responses. At longer time scales, smaller mutation supplies may in theory lead to larger improvements when distant high-fitness genotypes more rea...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Salverda, Merijn L. M., Koomen, Jeroen, Koopmanschap, Bertha, Zwart, Mark P., de Visser, J. Arjan G. M.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715772/
https://ncbi.nlm.nih.gov/pubmed/29133391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712999114
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