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Methods of Assessing STING Activation and Trafficking
The signaling adapter protein STING is crucial for the host immune response to cytosolic DNA and cyclic dinucleotides. Under basal conditions, STING resides on the endoplasmic reticulum (ER), but upon activation, it traffics through secretory pathway to cytoplasmic vesicles, where STING activates do...
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| Publicado no: | Methods Mol Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5715460/ https://ncbi.nlm.nih.gov/pubmed/28808969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7237-1_10 |
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