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A chimeric HS4 insulator–scaffold attachment region enhances transgene expression in transfected Chinese hamster ovary cells

Chinese hamster ovary (CHO) cells are one of the most commonly used expression systems for the production of recombinant proteins but low levels of transgene expression and transgene silencing are frequently encountered. Epigenetic regulatory elements such as the chicken β‐globin locus control regio...

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Detaylı Bibliyografya
Yayımlandı:FEBS Open Bio
Asıl Yazarlar: Chen, Si‐jia, Wang, Wen, Zhang, Feng‐yi, Jia, Yan‐long, Wang, Xiao‐yin, Guo, Xiao, Chen, Shao‐Nan, Gao, Jian‐hui, Wang, Tian‐Yun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715248/
https://ncbi.nlm.nih.gov/pubmed/29226088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12335
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