Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology

Organotypic co-cultures bridge the gap between standard two-dimensional culture and mouse models. Such assays increase the fidelity of pre-clinical studies, to better inform lead compound development and address the increasing attrition rates of lead compounds within the pharmaceutical industry, whi...

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Опубликовано в: :Sci Rep
Главные авторы: Conway, James R. W., Vennin, Claire, Cazet, Aurélie S., Herrmann, David, Murphy, Kendelle J., Warren, Sean C., Wullkopf, Lena, Boulghourjian, Alice, Zaratzian, Anaiis, Da Silva, Andrew M., Pajic, Marina, Morton, Jennifer P., Cox, Thomas R., Timpson, Paul
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715059/
https://ncbi.nlm.nih.gov/pubmed/29203823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17177-5
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