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P2X7R antagonism after subfailure overstretch injury of blood vessels reverses vasomotor dysfunction and prevents apoptosis

Human saphenous vein (HSV) is harvested and prepared prior to implantation as an arterial bypass graft. Injury and the response to injury from surgical harvest and preparation trigger cascades of molecular events and contribute to graft remodeling and intimal hyperplasia. Apoptosis is an early respo...

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Bibliografske podrobnosti
izdano v:Purinergic Signal
Main Authors: Luo, Weifeng, Feldman, Daniel, McCallister, Reid, Brophy, Colleen, Cheung-Flynn, Joyce
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714848/
https://ncbi.nlm.nih.gov/pubmed/28905300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-017-9585-0
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