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Reversal of cardiac dysfunction by selective ET-A receptor antagonism
1. The effectiveness of a selective endothelin receptor-A (ET-A) antagonist, A-127722 (approximately 10 mg kg(−1) day(−1) as 200 mg kg(−1) powdered food), to reverse existing cardiac remodelling and prevent further remodelling was tested in deoxycorticosterone acetate (DOCA)-salt hypertensive rats....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1751222/ https://ncbi.nlm.nih.gov/pubmed/16151437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706384 |
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