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Reversal of cardiac dysfunction by selective ET-A receptor antagonism

1. The effectiveness of a selective endothelin receptor-A (ET-A) antagonist, A-127722 (approximately 10 mg kg(−1) day(−1) as 200 mg kg(−1) powdered food), to reverse existing cardiac remodelling and prevent further remodelling was tested in deoxycorticosterone acetate (DOCA)-salt hypertensive rats....

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Autors principals: Allan, Anthony, Fenning, Andrew, Levick, Scott, Hoey, Andrew, Brown, Lindsay
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751222/
https://ncbi.nlm.nih.gov/pubmed/16151437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706384
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