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Pericellular regulation of prostate cancer expressed kallikrein-related peptidases and matrix metalloproteinases by cell surface serine proteases

We provide evidence of a pericellular network of proteases that are elevated and co-expressed in prostate cancer. The network involves the membrane bound serine proteases hepsin and TMPRSS2, the secreted kallikrein-related peptidases KLK4 and KLK14, and the secreted matrix metalloproteinases MMP-3 a...

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Dettagli Bibliografici
Pubblicato in:Am J Cancer Res
Autori principali: Reid, Janet C, Matsika, Admire, Davies, Claire M, He, Yaowu, Broomfield, Amy, Bennett, Nigel C, Magdolen, Viktor, Srinivasan, Bhuvana, Clements, Judith A, Hooper, John D
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714754/
https://ncbi.nlm.nih.gov/pubmed/29218249
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