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Activation Profiles of Human Kallikrein-related Peptidases by Matrix Metalloproteinases

The 15 human kallikrein-related peptidases (KLKs) are clinically important biomarkers and therapeutic targets of interest in inflammation, cancer and neurodegenerative disease. KLKs are secreted as inactive pro-forms (pro-KLKs) that are activated extracellularly by specific proteolytic release of th...

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Detalhes bibliográficos
Main Authors: Yoon, Hyesook, Blaber, Sachiko I., Li, Wu, Scarisbrick, Isobel A., Blaber, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709557/
https://ncbi.nlm.nih.gov/pubmed/23241590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/hsz-2012-0249
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