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Novel small molecule guanidine Sigma1 inhibitors for advanced prostate cancer
Prostate cancer is the most frequently diagnosed malignancy and the leading cause of cancer related death in men. First line therapy for disseminated disease relies on androgen deprivation, leveraging the addiction of these tumors on androgens for both growth and survival. Treatment typically involv...
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| Publicado no: | Bioorg Med Chem Lett |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5714280/ https://ncbi.nlm.nih.gov/pubmed/28385503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2017.03.030 |
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