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Is ascorbate Dr Jekyll or Mr Hyde in the Cu(Aβ) mediated oxidative stress linked to Alzheimer’s disease?†

Evaluation of the pro versus antioxidant activity of ascorbate regarding Cu(Aβ) induced reactive oxygen species production in the context of Alzheimer’s disease shows that a protective activity can only be observed at high ascorbate concentration for exogenous molecules but not for the amyloid-β pep...

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Dettagli Bibliografici
Pubblicato in:Dalton Trans
Autori principali: Cheignon, Clémence, Collin, Fabrice, Faller, Peter, Hureau, Christelle
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714186/
https://ncbi.nlm.nih.gov/pubmed/27264439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6dt01979j
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