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Amyloid-β Peptide: Dr. Jekyll or Mr. Hyde?
Amyloid-β peptide (Aβ) is considered a key protein in the pathogenesis of Alzheimer’s disease (AD) because of its neurotoxicity and capacity to form characteristic insoluble deposits known as senile plaques. Aβ derives from amyloid-β protein precursor (AβPP), whose proteolytic processing generates s...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3696497/ https://ncbi.nlm.nih.gov/pubmed/22735675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2012-129033 |
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