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A group II metabotropic glutamate receptor 3 (mGlu3, GRM3) isoform implicated in schizophrenia interacts with canonical mGlu3 and reduces ligand binding

As well as being expressed as a full-length transcript, the group II metabotropic glutamate receptor 3 (GRM3, mGlu3) gene is expressed as an mRNA isoform which lacks exon 4 (GRM3Δ4) and which is predicted to encode a protein with a novel C terminus (called mGlu3Δ4). This variant may contribute to th...

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Detalhes bibliográficos
Publicado no:J Psychopharmacol
Main Authors: García-Bea, Aintzane, Bermudez, Isabel, Harrison, Paul J, Lane, Tracy A
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714154/
https://ncbi.nlm.nih.gov/pubmed/28655286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881117715597
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