Decreased striatal dopamine in group II metabotropic glutamate receptor (mGlu2/mGlu3) double knockout mice

BACKGROUND: Group II metabotropic glutamate receptors (mGlu2 and mGlu3, encoded by Grm2 and Grm3) have been the focus of attention as treatment targets for a number of psychiatric conditions. Double knockout mice lacking mGlu2 and mGlu3 (mGlu2/3(−/−)) show a subtle behavioural phenotype, being hypoa...

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Détails bibliographiques
Auteurs principaux: Lane, Tracy A, Boerner, Thomas, Bannerman, David M, Kew, James NC, Tunbridge, Elizabeth M, Sharp, Trevor, Harrison, Paul J
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857325/
https://ncbi.nlm.nih.gov/pubmed/24053122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-14-102
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