Molecular Dynamics Simulations of the [2Fe–2S] Cluster-Binding Domain of NEET Proteins Reveal Key Molecular Determinants That Induce Their Cluster Transfer/Release

[Image: see text] The NEET proteins are a novel family of iron–sulfur proteins characterized by an unusual three cysteine and one histidine coordinated [2Fe–2S] cluster. Aberrant cluster release, facilitated by the breakage of the Fe–N bond, is implicated in a variety of human diseases, including ca...

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Publicado no:J Phys Chem B
Main Authors: Pesce, Luca, Calandrini, Vania, Marjault, Henri-baptiste, Lipper, Colin H., Rossetti, Gulia, Mittler, Ron, Jennings, Patricia A., Bauer, Andreas, Nechushtai, Rachel, Carloni, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5713697/
https://ncbi.nlm.nih.gov/pubmed/29086562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.7b10584
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