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Sirtuin 5 is required for mouse survival in response to cardiac pressure overload
In mitochondria, the sirtuin SIRT5 is an NAD(+)-dependent protein deacylase that controls several metabolic pathways. Although a wide range of SIRT5 targets have been identified, the overall function of SIRT5 in organismal metabolic homeostasis remains unclear. Given that SIRT5 expression is highest...
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| Veröffentlicht in: | J Biol Chem |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5712617/ https://ncbi.nlm.nih.gov/pubmed/28972174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.809897 |
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