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Role of NAD(+) and mitochondrial sirtuins in cardiac and renal diseases

The coenzyme nicotinamide adenine dinucleotide (NAD(+)) has key roles in the regulation of redox status and energy metabolism. NAD(+) depletion is emerging as a major contributor to the pathogenesis of cardiac and renal diseases and NAD(+) repletion strategies have shown therapeutic potential as a m...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Rev Nephrol
Prif Awduron: Hershberger, Kathleen A., Martin, Angelical S., Hirschey, Matthew D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508210/
https://ncbi.nlm.nih.gov/pubmed/28163307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneph.2017.5
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