Pretargeting of internalizing trastuzumab and cetuximab with a (18)F-tetrazine tracer in xenograft models

BACKGROUND: Pretargeting-based approaches are being investigated for radioimmunoimaging and therapy applications to reduce the effective radiation burden to the patient. To date, only a few studies have used short-lived radioisotopes for pretargeting of antibodies, and such examples with internalizi...

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Bibliografische gegevens
Gepubliceerd in:EJNMMI Res
Hoofdauteurs: Keinänen, Outi, Fung, Kimberly, Pourat, Jacob, Jallinoja, Vilma, Vivier, Delphine, Pillarsetty, NagaVara Kishore, Airaksinen, Anu J., Lewis, Jason S., Zeglis, Brian M., Sarparanta, Mirkka
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Berlin Heidelberg 2017
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712296/
https://ncbi.nlm.nih.gov/pubmed/29198065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-017-0344-6
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