A New Highly Reactive and Low Lipophilicity Fluorine-18 Labeled Tetrazine Derivative for Pretargeted PET Imaging

[Image: see text] A new (18)F-labeled tetrazine derivative was developed aiming at optimal radiochemistry, fast reaction kinetics in inverse electron-demand Diels–Alder cycloaddition (IEDDA), and favorable pharmacokinetics for in vivo bioorthogonal chemistry. The radiolabeling of the tetrazine was a...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:ACS Med Chem Lett
Päätekijät: Keinänen, Outi, Li, Xiang-Guo, Chenna, Naveen K., Lumen, Dave, Ott, Jennifer, Molthoff, Carla F. M., Sarparanta, Mirkka, Helariutta, Kerttuli, Vuorinen, Tapani, Windhorst, Albert D., Airaksinen, Anu J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2015
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4716598/
https://ncbi.nlm.nih.gov/pubmed/26819667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00330
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia