Radiosensitisation in vivo by histone deacetylase inhibition with no increase in early normal tissue radiation toxicity

As the population ages, more elderly patients require radiotherapy-based treatment for their pelvic malignancies, including muscle-invasive bladder cancer, as they are unfit for major surgery. Therefore, there is an urgent need to find radiosensitising agents minimally toxic to normal tissues, inclu...

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Vydáno v:Mol Cancer Ther
Hlavní autoři: Groselj, Blaz, Ruan, Jia-Ling, Scott, Helen, Gorrill, Jessica, Nicholson, Judith, Kelly, Jacqueline, Anbalagan, Selvakumar, Thompson, James, Stratford, Michael RL, Jevons, Sarah J, Hammond, Ester M, Scudamore, Cheryl L, Kerr, Martin, Kiltie, Anne E
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712223/
https://ncbi.nlm.nih.gov/pubmed/28839000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-0011
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