Noninvasive prenatal diagnosis of fetal aneuploidy by circulating fetal nucleated red blood cells and extravillous trophoblasts using silicon-based nanostructured microfluidics

BACKGROUND: Noninvasive prenatal testing (NIPT) based on cell-free DNA in maternal circulation has been accepted worldwide by the clinical community since 2011 but limitations, such as maternal malignancy and fetoplacental mosaicism, preclude its full replacement of invasive prenatal diagnosis. We p...

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Bibliografiske detaljer
Udgivet i:Mol Cytogenet
Main Authors: Huang, Chung-Er, Ma, Gwo-Chin, Jou, Hei-Jen, Lin, Wen-Hsiang, Lee, Dong-Jay, Lin, Yi-Shing, Ginsberg, Norman A., Chen, Hsin-Fu, Chang, Frank Mau-Chung, Chen, Ming
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Methodology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712079/
https://ncbi.nlm.nih.gov/pubmed/29213331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-017-0343-3
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