Noninvasive prenatal diagnosis of fetal aneuploidy by circulating fetal nucleated red blood cells and extravillous trophoblasts using silicon-based nanostructured microfluidics

BACKGROUND: Noninvasive prenatal testing (NIPT) based on cell-free DNA in maternal circulation has been accepted worldwide by the clinical community since 2011 but limitations, such as maternal malignancy and fetoplacental mosaicism, preclude its full replacement of invasive prenatal diagnosis. We p...

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Detalhes bibliográficos
Publicado no:Mol Cytogenet
Main Authors: Huang, Chung-Er, Ma, Gwo-Chin, Jou, Hei-Jen, Lin, Wen-Hsiang, Lee, Dong-Jay, Lin, Yi-Shing, Ginsberg, Norman A., Chen, Hsin-Fu, Chang, Frank Mau-Chung, Chen, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Methodology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712079/
https://ncbi.nlm.nih.gov/pubmed/29213331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-017-0343-3
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