Noninvasive prenatal diagnosis of fetal aneuploidy by circulating fetal nucleated red blood cells and extravillous trophoblasts using silicon-based nanostructured microfluidics

BACKGROUND: Noninvasive prenatal testing (NIPT) based on cell-free DNA in maternal circulation has been accepted worldwide by the clinical community since 2011 but limitations, such as maternal malignancy and fetoplacental mosaicism, preclude its full replacement of invasive prenatal diagnosis. We p...

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Bibliografski detalji
Izdano u:Mol Cytogenet
Glavni autori: Huang, Chung-Er, Ma, Gwo-Chin, Jou, Hei-Jen, Lin, Wen-Hsiang, Lee, Dong-Jay, Lin, Yi-Shing, Ginsberg, Norman A., Chen, Hsin-Fu, Chang, Frank Mau-Chung, Chen, Ming
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Methodology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5712079/
https://ncbi.nlm.nih.gov/pubmed/29213331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-017-0343-3
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