17β-Estradiol sensitizes ovarian surface epithelium to transformation by suppressing Disabled-2 expression

Estrogen replacement therapy increases the risk of human ovarian cancer and exogenous estradiol accelerates the onset of ovarian cancer in mouse models. This study uses primary cultures of mouse ovarian surface epithelium (OSE) to demonstrate that one possible mechanism by which estrogen accelerates...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Vuong, Nhung H., Salah Salah, Omar, Vanderhyden, Barbara C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711839/
https://ncbi.nlm.nih.gov/pubmed/29196616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16219-2
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