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17β-Estradiol sensitizes ovarian surface epithelium to transformation by suppressing Disabled-2 expression

Estrogen replacement therapy increases the risk of human ovarian cancer and exogenous estradiol accelerates the onset of ovarian cancer in mouse models. This study uses primary cultures of mouse ovarian surface epithelium (OSE) to demonstrate that one possible mechanism by which estrogen accelerates...

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書目詳細資料
發表在:Sci Rep
Main Authors: Vuong, Nhung H., Salah Salah, Omar, Vanderhyden, Barbara C.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711839/
https://ncbi.nlm.nih.gov/pubmed/29196616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16219-2
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