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The uncoupling of catalysis and translocation in the viral RNA-dependent RNA polymerase

The nucleotide addition cycle of nucleic acid polymerases includes 2 major events: the pre-chemistry active site closure leading to the addition of one nucleotide to the product chain; the post-chemistry translocation step moving the polymerase active site one position downstream on its template. In...

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Bibliografiske detaljer
Udgivet i:RNA Biol
Main Authors: Shu, Bo, Gong, Peng
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711473/
https://ncbi.nlm.nih.gov/pubmed/28277928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2017.1300221
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