Dynamical system modeling to simulate donor T cell response to whole exome sequencing-derived recipient peptides: Understanding randomness in alloreactivity incidence following stem cell transplantation

Quantitative relationship between the magnitude of variation in minor histocompatibility antigens (mHA) and graft versus host disease (GVHD) pathophysiology in stem cell transplant (SCT) donor-recipient pairs (DRP) is not established. In order to elucidate this relationship, whole exome sequencing (...

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Vydáno v:PLoS One
Hlavní autoři: Koparde, Vishal, Abdul Razzaq, Badar, Suntum, Tara, Sabo, Roy, Scalora, Allison, Serrano, Myrna, Jameson-Lee, Max, Hall, Charles, Kobulnicky, David, Sheth, Nihar, Feltz, Juliana, Contaifer, Daniel, Wijesinghe, Dayanjan, Reed, Jason, Roberts, Catherine, Qayyum, Rehan, Buck, Gregory, Neale, Michael, Toor, Amir
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711034/
https://ncbi.nlm.nih.gov/pubmed/29194460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187771
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