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Orienting the causal relationship between imprecisely measured traits using GWAS summary data
Inference about the causal structure that induces correlations between two traits can be achieved by combining genetic associations with a mediation-based approach, as is done in the causal inference test (CIT). However, we show that measurement error in the phenotypes can lead to the CIT inferring...
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| Publicado en: | PLoS Genet |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5711033/ https://ncbi.nlm.nih.gov/pubmed/29149188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007081 |
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