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Discovery of novel frizzled-7 inhibitors by targeting the receptor’s transmembrane domain
Frizzled (Fzd) proteins are seven transmembrane receptors that belong to a novel and separated family of G-protein-coupled receptors (GPCRs). The Fzd receptors can respond to Wnt proteins to activate the canonical β-catenin pathway which is important for both initiation and progression of cancers. D...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5710937/ https://ncbi.nlm.nih.gov/pubmed/29207657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20665 |
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